LEARNING OBJECTIVES
Evaluate the evidence and practical considerations for the selection and dosing of anticoagulants in patients with cancer and obesity, including limitations of current data and implications for direct oral anticoagulants (DOACs) and low molecular weight heparin (LMWH) use.
Examine evidence-based strategies for the management of recurrent thrombosis despite therapeutic anticoagulation, with a focus on treatment escalation, switching anticoagulant classes, and individualized risk assessment.
Discuss the approach to bleeding complications in patients with venous thromboembolism (VTE) receiving anticoagulation, including acute management, risk stratification, and decision-making regarding the timing and strategy for resumption of anticoagulation.